The variations in AA sequences permitted development of quantitative assays for cTnI/T. Most cTn assays are non-aggressive enzyme-linked immunosorbent assays (ELISA) based on the sandwich theory, making use of the superior specificity and affinity of antibodies.31 The assay is based on a capture antibody which binds to a specific epitope of cTn, al
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generates a number of alternatively spliced transcripts encoding distinct isoforms. Four distinct cTnT isoforms are produced via option splicing (selected cTnT1-four numbered as a way of decreasing molecular measurement), exactly where cTnT3 is the dominant isoform in the traditional adult heart.14 In combination with other proteins of your contrac
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